Personal profile
Research overview
I am a biophysicist with experience as a research microscopist, using scanning probe methods, then fluorescence fluctuations and super-resolution techniques. This expertise builds on top of training in solid-state physics, molecular electronics and semiconducting thin films matured working in Italy, Switzerland, the US, Germany and now the UK. Our team researches fundamental molecular mechanisms modulating cellular signalling using biophotonics and nanotechnology approaches.
Projects from former institutions
Education/Academic qualification
Doctor of Science, Investigating the Impact of Single Molecule Fluorescence Dynamics on Photo Activated Localization Microscopy Experiments, Swiss Federal Technology Institute of Lausanne
15 Oct 2008 → 15 Oct 2012
Award Date: 10 Oct 2012
External positions
Group Leader, Max Delbruck Center for Molecular Medicine
1 Jan 2020 → 31 Dec 2023
Keywords
- QC Physics
- QP Physiology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 9 Industry, Innovation, and Infrastructure
Fingerprint
- 1 Similar Profiles
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Cell swelling enhances ligand-driven β-adrenergic signaling
Sirbu, A., Bathe-Peters, M., Mahendra Kumar, J. L., Inoue, A., Lohse, M. J. & Annibale, P., 7 Sept 2024, In: Nature Communications. 15, 12 p., 7822.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes
Bathe-Peters, M., Gmach, P., Boltz, H. H., Einsiedel, J., Gotthardt, M., Hübner, H., Gmeiner, P., Lohse, M. J. & Annibale, P., 8 Jun 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 23, 10 p., e2101119118.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Fluorescence spectroscopy investigation of the temporal evolution of β-adrenergic receptors expression at the plasma membrane in differentiating human induced pluripotent stem cells
Annibale, P., Gmach, P., Bathe-Peters, M. & Telegu, N., 31 Dec 2022, In: Journal of Molecular and Cellular Cardiology. 173, supplement, p. S160 1 p.Research output: Contribution to journal › Abstract › peer-review
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The impact of membrane protein diffusion on GPCR signaling
Boltz, H.-H., Sirbu, A., Stelzer, N., de Lanerolle, P., Winkelmann, S. & Annibale, P., 17 May 2022, In: Cells. 11, 10, 18 p., 1660.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions
Fasciani, I., Petragnano, F., Wang, Z., Edwards, R., Telugu, N., Pietrantoni, I., Zabel, U., Zauber, H., Grieben, M., Terzenidou, M. E., Di Gregorio, J., Pellegrini, C., Santini, S., Taddei, A. R., Pohl, B., Aringhieri, S., Carli, M., Aloisi, G., Marampon, F. & Charlesworth, E. & 12 others, , 29 Apr 2024, In: PLoS Biology. 22, 4, 36 p., e3002582.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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S2 Data Figures
Annibale, P. (Creator), Petragnano, F. (Creator) & Wang, Z. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.25249912.v1
Dataset
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Quantitative morphological analysis of the T-tubular network of ventricular cardiomyocytes using novel image processing tools (code)
Annibale, P. (Creator), GitHub, 2025
https://github.com/kgeorgo/TTs_segmentation and one more link, https://github.com/Biomedical-Imaging-Group/OrientationJ. (show fewer)
Dataset: Software
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Single-molecule localization microscopy error is sensor dependent and larger than theory predicts (code)
Brenlla-Lopez, A. (Creator), Deen, L. (Creator) & Annibale, P. (Creator), GitHub, 2024
https://github.com/brenlla1/Localisation-precision
Dataset: Software
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Geometry and finesse: Bottom-up nanoscale control of compartmentalized cellular signaling: geometry and finesse
Annibale, P. (PI)
1/05/23 → 30/04/28
Project: Standard
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Optical tweezers-confocal microscope: A correlative, ultra-stable, optical tweezers-confocal microscope for high-resolution molecular and cellular mechanobiology
Penedo, C. (PI), Annibale, P. (CoI), Bruce, G. (CoI), Gather, M. (CoI), Guimaraes da Silva, R. (CoI), Melo Czekster, C. (CoI), O'Hagan, D. (CoI), Schwarz-Linek, U. (CoI), Smith, T. K. (CoI), Tilsner, J. (CoI), Varela, J. (CoI) & White, M. (CoI)
Biotechnology and Biological Sciences Research Council
1/08/23 → 31/07/24
Project: Standard
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Activities
- 1 Editor of research journal
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Biomolecules (Journal)
Annibale, P. (Member of editorial board)
1 Jan 2021 → 31 Mar 2022Activity: Publication peer-review and editorial work types › Editor of research journal