Research output per year
Research output per year
Personal profile
Research overview
Judith Sleeman is a former Royal Society University Research Fellow with key interests in the physical organisation of RNA processing in mammalian cells and the impact of this on human disease. Leading on from early work into the cellular organisation of splicing snRNP maturation, research in the Sleeman lab has expanded to include cytoplasmic transport of mRNA and the effects on cellular structure of triplet repeat disorders. Current projects in the group investigate the cellular and molecular basis of Spinal Muscular Atrophy, Myotonic Dystrophy Type 1 and Amyetrophic Lateral Sclerosis. Key techniques include live-cell and high-resolution microscopy and proteomics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where Judith Elizabeth Sleeman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
-
Condensation properties of stress granules and processing bodies are compromised in myotonic dystrophy type 1
Gulyurtlu, S., Magon, M. S., Guest, P. N., Papavasiliou, P. P., Morrison, K., Prescott, A. & Sleeman, J. E., 2 Aug 2022, In: Disease Models & Mechanisms. 15, 7, dmm049294.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The ‘most expensive drug in the world’, how it works and the devastating disease it treats
Sleeman, J. E., 19 Jul 2021, The Conversation.Research output: Contribution to specialist publication › Article
Open Access -
Neurochondrin interacts with the SMN protein suggesting a novel mechanism for Spinal Muscular Atrophy pathology
Thompson, L. W., Morrison, K. D., Shirran, S. L., Groen, E. J. N., Gillingwater, T. H., Botting, C. H. & Sleeman, J. E., 17 Apr 2018, In: Journal of Cell Science. 131, 8, 18 p., jcs211482.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The Cajal body and the nucleolus: “in a relationship” or “it's complicated”?
Trinkle-Mulcahy, L. & Sleeman, J. E., 2017, In: RNA Biology. 14, 6, p. 739-751Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Nuclear bodies: new insights into assembly/dynamics and disease relevance
Sleeman, J. E. & Trinkle-Mulcahy, L., Jun 2014, In: Current Opinion in Cell Biology. 28, p. 76-83 8 p.Research output: Contribution to journal › Article › peer-review
Datasets
-
Quantitative Interactomics to Identify Cellular Pathways Affected in Spinal Muscular Atrophy (Thesis Data)
Beaumont, B. (Creator) & Sleeman, J. E. (Creator), University of St Andrews, 26 Jul 2024
DOI: 10.17630/909d53bc-65a2-4c5c-97ec-f3b9e5552b28
Dataset: Thesis dataset
File -
Neurochondrin interacts with the SMN protein suggesting a novel mechanism for Spinal Muscular Atrophy pathology. (Mass spectrometry data)
Thompson, L. W. (Creator), Morrison, K. D. (Creator), Shirran, S. L. (Creator), Groen, E. J. N. (Creator), Gillingwater, T. H. (Creator), Botting, C. H. (Creator) & Sleeman, J. E. (Creator), PRIDE - PRoteomics IDEntifications database, 15 Mar 2018
https://www.ebi.ac.uk/pride/archive/projects/PXD008710
Dataset
Projects
- 10 Finished
-
Advanced integrative mass spectrometer: An advanced integrative mass spectrometer - the essential tool for in-depth analysis of diverse biological research.
Shirran, S. L. (PI), Evans, D. J. (CoI), Gloster, T. (CoI), Guimaraes da Silva, R. (CoI), Melo Czekster, C. (CoI), Powis, S. J. (CoI), Sleeman, J. E. (CoI), Smith, T. K. (CoI), Stewart, A. J. (CoI), Westwood, N. J. (CoI) & White, M. (CoI)
1/07/20 → 30/06/21
Project: Standard
-
ISSF3 studentship J Sleeman: Judith Sleeman Studentship ISSF3
Sleeman, J. E. (PI)
1/04/20 → 31/07/20
Project: Standard
-
Judith Sleeman MND Scotland: Protein methylation as a mechanism for cellular damage in motor neurone disease
Sleeman, J. E. (PI) & Miles, G. B. (CoI)
Motor Neurone Disease Scotland
2/03/20 → 1/03/22
Project: Standard
-
Activities
-
MNDA virtual 31st International Symposium on ALS/MND
Sleeman, J. E. (Participant)
9 Dec 2020 → 11 Dec 2020Activity: Participating in or organising an event types › Participation in or organising a conference
-
Elizabeth Garrett Mentoring Programme
Sleeman, J. E. (Participant)
2 Dec 2020 → …Activity: Participating in or organising an event types › Participation in or organising a workshop, seminar, course
-
BSRC seminar series
Sleeman, J. E. (Participant)
25 Nov 2020Activity: Participating in or organising an event types › Participation in or organising a workshop, seminar, course
-
UK SMA Research Consortium Virtual Symposium 2020
Sleeman, J. E. (Participant)
10 Sept 2020 → 11 Sept 2020Activity: Participating in or organising an event types › Participation in or organising a conference
-
CURE SMA
Sleeman, J. E. (Participant)
8 Jun 2020 → 12 Jun 2020Activity: Participating in or organising an event types › Participation in or organising a conference
Prizes
-
British Society for Cell Biology "Young Cell Biologist of the Year"
Sleeman, Judith Elizabeth (Recipient), 1995
Prize: Prize (including medals and awards)
-
-
Oxford Gene Technologies "Proof of Principle Micro-array Study" competition run at "BioScience2005", Glasgow.
Sleeman, Judith Elizabeth (Recipient), 2005
Prize: Prize (including medals and awards)
Press/Media
-
MDUK and Diana, Countess Lindsay, visit the Sleeman lab at the BSRC
20/06/18 → 22/06/18
2 items of Media coverage
Press/Media: Other
-
St Andrews scientists’ breakthrough on common genetic cause of infant death
18/04/18 → 25/04/18
4 items of Media coverage
Press/Media: Relating to Research