Research output per year
Research output per year
Personal profile
Research overview
Juan studied physics in Uruguay and did his PhD in Ireland at the Centre for Bio-Nano Interactions, University College Dublin. He subsequently did a postdoc at the Interdisciplinary Institute for Neurosciences in Bordeaux (France), and a second postdoc in neurodegeneration at the Department of Chemistry at the University of Cambridge (UK). Juan established his research group at the University of St Andrews funded by a European Research Council Starting Grant. His main research interests are the use of nanotechnology and single-molecule imaging to understand and cure neurodegenerative diseases. Visit our lab website for research updates and opportunities: https://neurophotonics.wp.st-andrews.ac.uk/
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Single-molecule imaging of aquaporin-4 array dynamics in astrocytes
Zepernick, A.-L., Metodieva, V., Pelegrina-Hidalgo, N., Lippert, A. H., Horrocks, M. H. & Varela, J. A., 21 May 2024, In: Nanoscale. 16, 19, p. 9576-9582 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Structure-specific amyloid precipitation in biofluids
Rodrigues, M., Bhattacharjee, P., Brinkmalm, A., Do, D. T., Pearson, C. M., De, S., Ponjavic, A., Varela, J. A., Kulenkampff, K., Baudrexel, I., Emin, D., Ruggeri, F. S., Lee, J. E., Carr, A. R., Knowles, T. P. J., Zetterberg, H., Snaddon, T. N., Gandhi, S., Lee, S. F. & Klenerman, D., Sept 2022, In: Nature Chemistry. 14, 9, p. 1045-1056 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
ThX-a next-generation probe for the early detection of amyloid aggregates
Needham, L. M., Weber, J., Varela, J. A., Fyfe, J. W. B., Do, D. T., Xu, C. K., Tutton, L., Cliffe, R., Keenlyside, B., Klenerman, D., Dobson, C. M., Hunter, C. A., Müller, K. H., O'Holleran, K., Bohndiek, S. E., Snaddon, T. N. & Lee, S. F., 14 May 2020, In: Chemical Science. 11, 18, p. 4578-4583 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms
De, S., Wirthensohn, D. C., Flagmeier, P., Hughes, C., Aprile, F. A., Ruggeri, F. S., Whiten, D. R., Emin, D., Xia, Z., Varela, J. A., Sormanni, P., Kundel, F., Knowles, T. P. J., Dobson, C. M., Bryant, C., Vendruscolo, M. & Klenerman, D., 4 Apr 2019, In: Nature Communications. 10, 11 p., 1541.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Comparative Analysis of Photoluminescence and Upconversion Emission from Individual Carbon Nanotubes for Bioimaging Applications
Danne, N., Godin, A. G., Gao, Z., Varela, J. A., Groc, L., Lounis, B. & Cognet, L., 21 Feb 2018, In: ACS Photonics. 5, 2, p. 359-364 11 p.Research output: Contribution to journal › Article › peer-review
Datasets
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Data underpinning Anna-Lena Zepernick's thesis
Zepernick, A.-L. (Creator) & Varela, J. A. (Supervisor), University of St Andrews, 22 Apr 2029
DOI: 10.17630/d699cbbe-fbab-454a-8377-9941d5df7c29, https://doi.org/10.17630/sta/862
Dataset: Thesis dataset
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Raw data for Qamar et al, FUS Phase Separation, Cell-D-17-01483
Qamar, S. (Creator), Wang, G. (Creator), Randle, S. J. (Creator), Ruggeri, F. S. (Creator), Varela, J. A. (Creator), Lin, J. Q. (Creator), Phillips, E. C. (Creator), Miyashita, A. (Creator), Williams, D. (Creator), Ströhl, F. (Creator), Meadows, W. (Creator), Ferry, R. (Creator), Dardov, V. J. (Creator), Tartaglia, G. G. (Creator), Farrer, L. A. (Creator), Kaminski Schierle, G. S. (Creator), Kaminski, C. F. (Creator), Holt, C. E. (Creator), Fraser, P. E. (Creator), Schmitt-Ulms, G. (Creator), Klenerman, D. (Creator), Knowles, T. (Creator), Vendruscolo, M. (Creator) & St George-Hyslop, P. (Creator), Mendeley Data, 30 Mar 2018
Dataset
Projects
- 5 Finished
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Optical tweezers-confocal microscope: A correlative, ultra-stable, optical tweezers-confocal microscope for high-resolution molecular and cellular mechanobiology
Penedo, C. (PI), Annibale, P. (CoI), Bruce, G. D. (CoI), Gather, M. C. (CoI), Guimaraes da Silva, R. (CoI), Melo Czekster, C. (CoI), O'Hagan, D. (CoI), Schwarz-Linek, U. (CoI), Smith, T. K. (CoI), Tilsner, J. (CoI), Varela, J. A. (CoI) & White, M. (CoI)
1/08/23 → 31/07/24
Project: Standard
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Juan Varela ISSF3 round 6: Juan Varela ISSF3 round 6
Varela, J. A. (PI)
1/04/21 → 31/03/22
Project: Standard
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Study interactions between SARS-CoV-2: A platform to study interactions between SARS-CoV-2 Spike and ACE2 receptor at the single-molecule level
Varela, J. A. (PI)
1/12/20 → 31/05/21
Project: Standard
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BrainNanoFlow: Nanoscale dynamics: H2020 ERC Starting Grant 2018 BrainNanoFlow Juan Varela
Varela, J. A. (PI)
1/12/18 → 30/11/23
Project: Fellowship