Research output per year
Research output per year
Personal profile
Research overview
Cytoskeletal assembly during tissue morphogenesis
Investigations deal mainly with the roles of microtubule-organizing centres during the development of certain animal tissues. Microtubule assembly during tissue morphogenesis and in reponse to experimentally induced perturbations is largely monitored using transmission electron microscopy and fluorescence microscopy in conjunction with antibodies and green fluorescent protein. Current studies are mainly concerned with control of microtubule positioning during cell differentiation in primary embryonic Drosophila cell cultures.
My studies of microtubules have involved investigations of the following fundamental cell functions, on occasion: mitosis, anaphase chromosome movement, cell division, cleavage furrow formation, cell motility, cell locomotion, cell shaping, cytoplasmic streaming, endocytosis, tissue morphogenesis, positioning of centrioles and basal bodies, organelle assembly and replication, deployment of microfilaments and intermediate filaments, cell adhesion, collagen secretion and alignment, and oogenesis
Future research
Control of the positioning of cell surface-associated microtubules.
Academic/Professional Qualification
M.A., University of Cambridge; Ph.D., University of Cambridge; B.A., University of Cambridge; British Society for Cell Biology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output
- 7 Article
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Positioning and capture of cell surface-associated microtubules in epithelial tendon cells that differentiate in primary embryonic Drosophila cell cultures
Tucker, J. B., Mackie, J., Cottam, D., Rogers-Bald, M., Macintyre, J., Scarborough, J. & Milner, M. J., Mar 2004, In: Cell Motility and the Cytoskeleton. 57, 3, p. 175-185 11 p.Research output: Contribution to journal › Article › peer-review
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The adenomatous polyposis coli protein unambiguously localises to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarised epithelial cells.
Mogensen, M., Tucker, J. B., Mackie, J., Prescott, A. & Nathke, I., 10 Jun 2002, In: Journal of Cell Biology. 157, p. 1041-1048 8 p.Research output: Contribution to journal › Article › peer-review
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Involvement of the Adenomatous Polyposis Coli Protein in establishing polar microtubule arrays in the inner ear epithelium
Mogensen, M. M., Tucker, J. B., Mackie, J. B., Prescott, A. R. & Nathke, I. S., Nov 2001, In: Molecular Biology of the Cell. 12, 1 p.Research output: Contribution to journal › Article › peer-review
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Cytoskeletal integration in a highly ordered sensory epithelium in the organ of Corti: response to loss of cell partners in the Bronx waltzer mouse
Tucker, J. B., Mackie, J., Bussoli, T. & Steel, K., Dec 1999, In: Journal of Neurocytology. 28, p. 1017-1034 18 p.Research output: Contribution to journal › Article › peer-review
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Keratin filament deployment and cytoskeletal networking in a sensory epithelium that vibrates during hearing
Tucker, J. B., Mogensen, M., Henderson, C., Mackie, J. & 2, O., 1998, In: Cell Motility and the Cytoskeleton. 41, p. 138-153 16 p.Research output: Contribution to journal › Article › peer-review
Activities
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Give presentations during Visiting Days (13 or so per annum) in my capacity as member of the School's External Relations Committee
Tucker, J. B. (Participant)
2005 → …Activity: Participating in or organising an event types › Participation in or organising a public festival/exhibition/event
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SERC Molecular Biology and Genetics Subcommittee (External organisation)
Tucker, J. B. (Participant)
1986 → 1989Activity: Membership types › Membership of peer review panel or committee
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Development (Journal)
Tucker, J. B. (Editor)
1978 → 1988Activity: Publication peer-review and editorial work types › Editor of research journal
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Science Research Council (SRC) Advisory Group II (External organisation)
Tucker, J. B. (Participant)
1977 → 1980Activity: Membership types › Membership of peer review panel or committee
Prizes
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Fellow of the Royal Society of Edinburgh
Tucker, J. B. (Recipient), 1996
Prize: Election to learned society