Personal profile
Research overview
I develop and apply mathematical and computational methodology to understand questions in developmental biology. I research how individual cells make decisions, for example to divide or differentiate, and how multiple cells interact to form healthy and viable tissues. My work includes analysing the dynamics of gene regulatory interactions and modelling mechanics of single cells and their interactions. My aim is to to decipher the fundamental mechanisms that underly the robustness of patterning and morphogenesis.
Education/Academic qualification
Doctor of Philosophy, Quantitative approaches to investigating epithelial morphogenesis, University of Oxford
Award Date: 1 Sept 2017
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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An active matter model captures spatial dynamics of actomyosin oscillations in larval epithelial cells during Drosophila morphogenesis
Mackay, E., Bebbington, A., Januschke, J., Kursawe, J., Bischoff, M. & Sknepnek, R., 20 Jan 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 3, p. 1-12 12 p., e2503955123.Research output: Contribution to journal › Article › peer-review
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Efficient approximations of transcriptional bursting effects on the dynamics of a gene regulatory network
Kursawe, J., Moneyron, A. & Galla, T., 25 Jun 2025, In: Journal of the Royal Society Interface. 22, 227, 16 p., 20250170.Research output: Contribution to journal › Article › peer-review
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Estimating full-field displacement in biological images using deep learning
Warsop, S. J. E. T., Caixeiro , S., Bischoff, M., Kursawe, J., Bruce, G. D. & Wijesinghe, P., 4 Jun 2025, In: npj Artificial Intelligence. 1, 12 p., 6.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
An active matter model captures the spatial dynamics of actomyosin oscillations during morphogenesis
Mackay, E. D., Bebbington, A., Januschke, J., Kursawe, J., Bischoff, M. & Sknepnek, R., 5 Oct 2024, bioRxiv, 33 p.Research output: Working paper › Preprint
Open Access -
Simulating BRAFV600E-MEK-ERK signalling dynamics in response to vertical inhibition treatment strategies
De Carli, A., Kapelyukh, Y., Kursawe, J., Chaplain, M. A. J., Wolf, C. R. & Hamis, S. J., 15 May 2024, In: npj Systems Biology and Applications. 10, 12 p., 51.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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Contributions of cell behavior to geometric order in embryonic cartilage (code)
Mathias, S. (Creator) & Kursawe, J. (Creator), GitHub, 2023
https://github.com/somathias/CartilageCBM/
Dataset: Software
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Simulating BRAFV600E-MEK-ERK signalling dynamics in response to vertical inhibition treatment strategies (code)
Kursawe, J. (Creator), Chaplain, M. A. J. (Creator) & Hamis, S. J. (Creator), GitHub, 2024
https://github.com/SJHamis/MAPKcascades
Dataset: Software
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Biga2020 is a repository for code used in the paper: "A dynamic, spatially periodic, micro-pattern of HES5 underlies neurogenesis in the mouse spinal cord" (dataset)
Biga, V. (Creator), Hawley, J. (Creator), Soto, X. (Creator), Johns, E. (Creator), Han, D. (Creator), Bennett, H. (Creator), Adamson, A. D. (Creator), Kursawe, J. (Creator), Glendinning, P. (Creator), Manning, C. S. (Creator) & Papalopulu, N. (Creator), GitHub, 2021
https://github.com/Papalopulu-Lab/Biga2020
Dataset: Software
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An active matter model captures spatial dynamics of actomyosin oscillations in larval epithelial cells during Drosophila morphogenesis
Sknepnek, R. (Creator), Mackay, E. (Creator), Bebbington, A. (Creator), Januschke, J. (Creator), Kursawe, J. (Creator) & Bischoff, M. (Creator), Zenodo, 2025
Dataset