Research output per year
Research output per year
Personal profile
Research overview
Measuring nanometre distances for structural biology using EPR spectroscopy.
I use Electron Paramagnetic Resonance (EPR) spectroscopy to measure nanometre distances in proteins and nucleic acids. This provides detail on their structure and dynamics. The methodology is applied to a range of proteins including those for protein excretion in the cell. I am also interested in developing the methods for tagging proteins and nucleic acids to make them suitable for this kind of investigation, as well as advancing the EPR experiments themselves.
The biological preparation and EPR facilities at St Andrews are outstanding with, among others, pulsed and CW X-band, high power Q-band and the home-built high power W-band (HiPER).
Research interests
Structure determination of proteins and protein complexes using distance measurements derived from EPR spectroscopy. New spin labels for cysteine rich proteins.
Academic/Professional Qualification
MChem (Oxon) 2002
DPhil 2006
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where Janet Eleanor Lovett is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Conformational tuning improves the stability of spirocyclic nitroxides with long paramagnetic relaxation times
Sowiński, M. P., Gahlawat, S., Lund, B. A., Warnke, A.-L., Hopmann, K. H., Lovett, J. E. & Haugland, M. M., 5 Jun 2023, In: Communications Chemistry. 6, 1, 8 p., 111.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Design of the elusive proteinaceous oxygen donor copper site suggests a promising future for copper for MRI contrast agents
Shah, A., Taylor, M. J., Molinaro, G., Anbu, S., Verdu, M., Jennings, L., Mikulska, I., Diaz-Moreno, S., El Mkami, H., Smith, G. M., Britton, M. M., Lovett, J. E. & Peacock, A. F. A., 4 Jul 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 27, e2219036120.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The photochemical mediated ring contraction of 4H-1,2,6-thiadiazines to afford 1,2,5-thiadiazol-3(2H)-one 1-oxides
Broumidis, E., Thomson, C. G., Gallagher, B., Sotorríos, L., McKendrick, K. G., Macgregor, S. A., Paterson, M. J., Lovett, J. E., Lloyd, G. O., Rosair, G. M., Kalogirou, A. S., Koutentis, P. A. & Vilela, F., 22 Sept 2023, In: Organic Letters. 25, 37, p. 6907-6912 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Triggered functional dynamics of AsLOV2 by time-resolved electron paramagnetic resonance at high magnetic fields
Maity, S., Price, B. D., Wilson, C. B., Mukherjee, A., Starck, M., Parker, D., Wilson, M. Z., Lovett, J. E., Han, S. & Sherwin, M. S., 20 Mar 2023, In: Angewandte Chemie International Edition. 62, 13, 9 p., e202212832.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Combined pulsed electron double resonance EPR and molecular dynamics investigations of calmodulin suggest effects of crowding agents on protein structures
Stewart, A., Shanmugam, M., Kutta, R., Scrutton, N., Lovett, J. E. & Hay, S., 6 Sept 2022, In: Biochemistry. 61, 17, p. 1735–1742 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
-
Versatile para-substituted pyridine lanthanide coordination complexes allow late stage tailoring of complex function (dataset)
Starck, M. (Creator), Batsanov, A. (Creator), Fradgley, J. (Creator), de Rosa, D. (Creator), Papa, M. (Creator), Taylor, M. J. (Creator), Lovett, J. E. (Creator) & Parker, D. (Creator), University of St Andrews, 24 Nov 2021
DOI: 10.17630/128d8c87-d13a-45d8-a5f2-5d5422b14d1a
Dataset
File -
Under Pressure: Measuring Nanometre Distance Changes in Biomolecules (thesis data)
Russell, H. (Creator) & Lovett, J. E. (Supervisor), University of St Andrews, 21 Apr 2026
DOI: 10.17630/74f265b7-6e42-4b3d-8ac2-20bc3e5c7d97, https://doi.org/10.17630/sta/865
Dataset: Thesis dataset
-
Design of the elusive proteinaceous oxygen donor copper site suggests a promising future for copper for MRI contrast agents (dataset)
Shah, A. (Creator), Taylor, M. J. (Creator), El Mkami, H. (Creator), Smith, G. M. (Creator) & Lovett, J. E. (Creator), University of St Andrews, 31 Jul 2023
DOI: 10.17630/835ab42b-5999-4437-8ccb-34cdc630a179
Dataset
File -
Unveiling the structure of RNA using EPR Spectroscopy (thesis data)
Papa, M. (Creator) & Lovett, J. E. (Supervisor), University of St Andrews, 29 Apr 2025
DOI: 10.17630/0071ab41-ddcb-4a7c-8806-c79c890b8316, https://doi.org/10.17630/sta/457
Dataset: Thesis dataset
-
DEER and RIDME Datasets for Calmodulin1 Variants (thesis dataset)
Fisher, S. R. (Creator) & Lovett, J. E. (Supervisor), University of St Andrews, 22 Aug 2024
DOI: 10.17630/90d0e0d0-e972-4a03-996a-3ef9e075db1a, https://doi.org/10.17630/sta/570
Dataset: Thesis dataset
File
-
Supramolecular structure predictions: Supramolecular Structure Predictions Validated from Sparse Experimental Data
Smith, G. M. (PI) & Lovett, J. E. (CoI)
1/11/22 → 31/10/25
Project: Standard
-
Enabling Shaped Pulse Capability: Enabling Shaped Pulse Capability for Superior Biological Structural Determination Using EPR Spectroscopy.
Lovett, J. E. (PI), Bode, B. E. (CoI), Penedo, C. (CoI), Pitt, S. J. (CoI), Schwarz-Linek, U. (CoI), Smith, G. M. (CoI), Watson, A. J. B. (CoI) & White, M. (CoI)
1/10/20 → 30/09/21
Project: Standard
-
EPSRC IAA - Birmingham Collaboration: EPSRC IAA - Birmingham Collaboration - Anokhi Shah
Lovett, J. E. (PI)
1/04/19 → 30/06/19
Project: Standard
-
Enabling Recision Distance: Enabling Recision Distance Measurements in Long RNAs
Lovett, J. E. (PI)
1/10/18 → 30/11/19
Project: Standard
-
Cryogen-free arbitrary waveform EPR: Cryogen-free arbitrary waveform EPR for structural Biology and Biophysics
Bode, B. E. (PI), Lovett, J. E. (CoI), Pliotas, C. (CoI), Schwarz-Linek, U. (CoI), Smith, G. M. (CoI), Stewart, A. J. (CoI) & White, M. (CoI)
1/05/18 → 30/04/19
Project: Standard
Activities
-
Science Discovery Day 2021
Lovett, J. E. (Participant)
6 Mar 2021Activity: Participating in or organising an event types › Participation in or organising a public festival/exhibition/event
-
School of Physics and Astronomy (Organisational unit)
Lovett, J. E. (Participant)
1 Jan 2021 → …Activity: Membership types › Membership of peer review panel or committee
-
EPR is a complementary technique in structural biology
Lovett, J. E. (Speaker)
1 Oct 2020Activity: Talk or presentation types › Invited talk
-
University of Bonn (External organisation)
Lovett, J. E. (Participant)
17 Sept 2020 → …Activity: Membership types › Membership of peer review panel or committee
-
White Paper on DEER/PELDOR
Lovett, J. E. (Speaker)
17 Sept 2020Activity: Talk or presentation types › Invited talk