Personal profile
Education/Academic qualification
Doctor of Philosophy, Mechanistic and proteomic exploration of the ISG15 modification pathway
Sept 2021 → Jan 2026
Award Date: 31 Jan 2026
Master in Science, MSci Molecular and Cellular Biology (with Plant Science), University of Glasgow
Sept 2016 → Jun 2021
Award Date: 1 Jun 2021
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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ISGylation is disrupted by UBA7 gene variants identified in individuals with neurodevelopmental disorder phenotypes.
Bandi, V., Venema, M., Wallace, I., Mol, M. O., Nikoncuk, A., Schot, R., van Slegtenhorst, M., Bijlsma, E., Khan, A., White, S. M., Rius, R., Delatycki, M. B., Narayanan, V., Swatek, K. N., Barakat, T. S. & Bustos, F., 30 Mar 2026, (E-pub ahead of print) In: iScience. In Press, 115454.Research output: Contribution to journal › Article › peer-review
Open Access -
Phosphorylation enables progressive microtubule-associated protein proteolysis and functionalisation during neural development
Yang, Z., Liczmanska, M., Hogg, E. K. J., Wallace, I., Zhou, H., Gourlay, R., Squires, I., Li, Z., Hao, Y., Brown, F., Toth, R., Macartney, T., Hastie, C. J., Qi, Y. A., Gierlinski, M., Bustos, F. & Findlay, G. M., 20 Sept 2025, bioRxiv, p. 1-59, 59 p.Research output: Working paper › Preprint
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VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains
Lange, S. M., McFarland, M. R., Lamoliatte, F., Carroll, T., Krshnan, L., Pérez-Ràfols, A., Kwasna, D., Shen, L., Wallace, I., Cole, I., Armstrong, L. A., Knebel, A., Johnson, C., De Cesare, V. & Kulathu, Y., Dec 2024, In: Nature Structural and Molecular Biology. 31, 12, p. 1872-1887 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
CardioMotion: identification of functional and structural cardiotoxic liabilities in small molecules through brightfield kinetic imaging
Stebbeds, W., Raniga, K., Standing, D., Wallace, I., Bayliss, J., Brown, A., Kasprowicz, R., Dalmas Wilk, D., Deakyne, J., Clements, P., Chaudhary, K. W., Rossman, E. I., Bahinski, A. & Francis, J., Sept 2023, In: Toxicological Sciences. 195, 1, p. 61-70 10 p.Research output: Contribution to journal › Article › peer-review
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Insights into the ISG15 transfer cascade by the UBE1L activating enzyme
Wallace, I., Baek, K., Prabu, J. R., Vollrath, R., von Gronau, S., Schulman, B. A. & Swatek, K. N., 2 Dec 2023, In: Nature Communications. 14, p. 1-13 13 p., 7970.Research output: Contribution to journal › Article › peer-review
Open Access