Personal profile
Research overview
My research interests are broadly in evolution and development, with a focus on comparative mechanisms between embryonic processes and regeneration. The main body of my work is carried out in the cephalochordate amphioxus, an invertebrate chordate that is fast emerging as an important model system for understanding the evolution of vertebate characters from an invertebrate ancestor. This is largely facilitated by its "prototypical" genome organisation and simple chordate morphology. The fact that amphioxus regenerates complex structures well as an adult also holds promise for its use as a regeneration model system.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 7 Affordable and Clean Energy
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SDG 14 Life Below Water
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Collaborations and top research areas from the last five years
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Adult stem cells host intracellular symbionts: the poriferan archetype
Ereskovsky, A., Rinkevich, B. & Somorjai, I. M. L., 1 Feb 2022, Advances in aquatic invertebrate stem cell research: from basic research to innovative applications. Ballarin, L., Rinkevich, B. & Hobmayer, B. (eds.). Basel: MDPI, p. 65-93 29 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Epidermal changes during tail regeneration in the Bahamas lancelet, Asymmetron lucayanum (Cephalochordata)
Holland, N. D. & Somorjai, I. M. L., 1 Jul 2022, In: Acta Zoologica. 103, 3, p. 297-306 10 p.Research output: Contribution to journal › Article › peer-review
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Three-dimensional fine structure of fibroblasts and other mesodermally derived tissues in the dermis of adults of the Bahamas lancelet (Chordata, Cephalohordata), as seen by serial block-face scanning electron microscopy
Holland, N. D., Holland, L. Z. & Somorjai, I. M. L., 1 Oct 2022, In: Journal of Morphology. 283, 10, p. 1289-1298 10 p.Research output: Contribution to journal › Article › peer-review
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A pan-metazoan concept for adult stem cells: the wobbling Penrose landscape
Rinkevich, B., Ballarin, L., Martinez, P., Somorjai, I. M. L., Ben-Hamo, O., Borisenko, I., Berezikov, E., Ereskovsky, A., Gazave, E., Khnykin, D., Manni, L., Petukhova, O., Rosner, A., Röttinger, E., Spagnuolo, A., Sugni, M., Tiozzo, S. & Hobmayer, B., 6 Oct 2021, (E-pub ahead of print) In: Biological Reviews. Early View, 27 p.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile -
JNK mediates differentiation, cell polarity and apoptosis during amphioxus development by regulating actin cytoskeleton dynamics and ERK signalling
Somorjai, I. M. L., Ehebauer, M. T., Escriva, H. & Garcia-Fernandez, J., 29 Oct 2021, In: Frontiers in Cell and Developmental Biology. 9, 24 p., 749806.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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Data underpinning: Light sheet microscopy with acoustic sample confinement
Nylk, J. (Creator), Yang, Z. (Creator), Cole, K. (Creator), Qiu, Y. (Creator), Somorjai, I. M. L. (Creator), Wijesinghe, P. (Creator), Cochran, S. (Creator), Spalding, G. (Creator), Lyons, D. (Creator) & Dholakia, K. (Creator), University of St Andrews, 27 Apr 2022
DOI: 10.17630/cc36c86a-5ed5-4198-8c93-52310dcf979c
Dataset
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The Role of Biological Shape in Optical and Acoustic Measurements (thesis data)
Bairstow, F. J. (Creator), Brown, C. T. A. (Supervisor) & Somorjai, I. M. L. (Supervisor), University of St Andrews, 1 Sept 2022
DOI: 10.17630/f0f023b5-2688-4cda-bef9-bbd7460671a1, https://doi.org/10.17630/sta/352
Dataset: Thesis dataset
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Wnt evolution and function shuffling in liberal and conservative chordate genomes
Somorjai, I. M. L. (Creator), Marti-Solans, J. (Creator), Diaz-Gracia, M. (Creator), Escriva, H. (Creator), Cañestro, C. (Creator), Nishida, H. (Creator), Imai, K. S. (Creator) & Albalat, R. (Creator), Figshare, 12 Jun 2018
DOI: 10.6084/m9.figshare.6477494.v1
Dataset
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A revised spiralian homeobox gene classification incorporating new polychaete transcriptomes reveals a diverse TALE class and a divergent Hox gene (dataset)
Barton-Owen, T. (Creator), Szabó, R. (Creator), Somorjai, I. M. L. (Creator) & Ferrier, D. E. K. (Creator), National Center for Biotechnology Information, 11 Dec 2018
https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA433343
Dataset
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Amphioxus functional genomics and the origins of vertebrate gene regulation (next-generation sequencing data)
Marletaz, F. (Creator), Firbas, P. (Creator), Maeso, I. (Creator), Tena, J. (Creator), Bogdanovic, O. (Creator), Perry, M. (Creator), Wyatt, C. (Creator), de la Calle-Mustienes, E. (Creator), Bertrand, S. (Creator), Burguera, D. (Creator), Acemel, R. (Creator), van Heeringen, S. (Creator), Naranjo, S. (Creator), Herrera-Ubeda, C. (Creator), Skvortsova, K. (Creator), Jimenez-Gancedo, S. (Creator), Aldea, D. (Creator), Marquez, Y. (Creator), Buono, L. (Creator), Kozmikova, I. (Creator), Permanyer, J. (Creator), Louis, A. (Creator), Albuixech-Crespo, B. (Creator), Le Petillon, Y. (Creator), Leon Florian, A. (Creator), Subirana, L. (Creator), Balwierz, P. J. (Creator), Duckett, P. (Creator), Farahani, E. (Creator), Aury, J. M. (Creator), Mangenot, S. (Creator), Wincker, P. (Creator), Albalat, R. (Creator), Benito-Gutierrez, E. (Creator), Canestro, C. (Creator), Castro, F. (Creator), D'Aniello, S. (Creator), Ferrier, D. E. K. (Creator), Huang, S. (Creator), Laudet, V. (Creator), Marais, G. (Creator), Pontarotti, P. (Creator), Schubert, M. (Creator), Seitz, H. (Creator), Somorjai, I. M. L. (Creator), Takahashi, T. (Creator), Mirabeau, O. (Creator), Xu, A. (Creator), Yu, J.-K. (Creator), Carninci, P. (Creator), Martinez-Morales, J. (Creator), Crollius, H. (Creator), Kozmik, Z. (Creator), Weirauch, M. (Creator), Garcia-Fernandez, J. (Creator), Lister, R. (Creator), Lenhard, B. (Creator), Holland, P. (Creator), Escriva, H. (Creator), Gomez-Skarmeta, J. L. (Creator) & Irimia, M. (Creator), Gene Expression Omnibus (GEO), 15 Aug 2018
http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106372 and 5 more links, http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106428, http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106429, http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106430, http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE102144, http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE115945 (show fewer)
Dataset
Projects
- 5 Finished
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Ildiko Somorjai seedcorn funding: Ildiko Somorjai
Somorjai, I. (PI)
1/05/20 → 30/04/21
Project: Standard
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ASSEMBLE Plus: H2020 INFRA ASSEMBLE
Somorjai, I. (PI)
European Commission Joint Research Centre
1/10/17 → 30/09/21
Project: Standard
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CORBEL: H2020 INFRADEV4
Ferrier, D. (PI) & Somorjai, I. (CoI)
European Commission Joint Research Centre
1/09/15 → 31/05/20
Project: Standard
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Reserved for Ildiko Somorjai: Development of transgenesis in amphioxus for lineage analysis in regeneration adult tails
Somorjai, I. (PI)
31/12/14 → 30/12/16
Project: Standard
Activities
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Genes, Cells and Embryos in Development and Evolution
Somorjai, I. M. L. (Participant)
9 Nov 2023 → 10 Nov 2023Activity: Participating in or organising an event types › Participation in or organising a conference
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New question, new model
Somorjai, I. M. L. (Speaker)
29 Jun 2023 → 2 Jul 2023Activity: Talk or presentation types › Presentation
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DevBioCat synergy Meeting
Somorjai, I. M. L. (Participant)
10 Feb 2023Activity: Participating in or organising an event types › Participation in or organising a conference
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Amphioxus and the Metazoan Stem Cell Concept
Somorjai, I. M. L. (Speaker)
12 May 2022Activity: Talk or presentation types › Invited talk
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Development Genes and Evolution (Journal)
Somorjai, I. M. L. (Member of editorial board)
2021 → …Activity: Publication peer-review and editorial work types › Editor of research journal
Prizes
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Fellow of the Royal Society of Biology
Somorjai, I. M. L. (Recipient), 2018
Prize: Election to learned society