Research output per year
Research output per year
Personal profile
Research overview
PhD student with Professor David Harrison and Dr Alison Dickson developing a multi-modal imaging workflow by applying Mass spectrometry Imaging, Histology and Immunolabeling on a single human tissue section to study the metabolic crosstalk in the tumour microenvironment of clear cell Renal Cell Carcinoma (ccRCC).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where Greice Michele Zickuhr is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Probing the human 4-oxo-L-proline reductase-catalysed reaction by deuterium kinetic and equilibrium isotope effects
Pečaver, E., Kabu, M., Zickuhr, G. M., Harrison, D. J. & da Silva, R. G., 4 Aug 2026, In: Biochemistry. 65, 15, p. 2419-2430 12 p.Research output: Contribution to journal › Article › peer-review
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Improved nucleoside (2'-deoxy)ribosyltransferases maximize enzyme promiscuity while maintaining catalytic efficiency
Tang, P., Zickuhr, G. M., Dickson, A. L., Harding, C. J., Devi, S., Lebl, T., Harrison, D. J., da Silva, R. G. & Melo Czekster, C., 21 Nov 2025, In: ACS Chemical Biology. 20, 11, p. 2547–2553 7 p.Research output: Contribution to journal › Letter › peer-review
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Kidney tumoroid characterisation by spatial mass spectrometry with same-section multiplex immunofluorescence uncovers tumour microenvironment lipid signatures associated with aggressive tumour phenotypes
Abdullah, H., Zickuhr, G. M., Um, I. H., Laird, A., Mullen, P., Harrison, D. J. & Dickson, A. L., 16 Sept 2025, In: npj Imaging. 3, p. 1-11 11 p., 43.Research output: Contribution to journal › Article › peer-review
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Kinetic and thermodynamic characterization of human 4-oxo-L-proline reductase catalysis
Pecaver, E., Zickuhr, G. M., Machado, T. F. G., Harrison, D. J. & da Silva, R. G., 18 Feb 2025, In: Biochemistry. 64, 4, p. 860-870 11 p.Research output: Contribution to journal › Article › peer-review
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Defining the mode of action of cisplatin combined with NUC-1031, a phosphoramidate modification of gemcitabine
Patel, D., Dickson, A., Zickuhr, G. M., Um, I. H., Read, O. J., Melo Czekster, C., Mullen, P., Harrison, D. J. & Bre, J. L., 1 Dec 2024, In: Translational Oncology. 50, 11 p., 102114.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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HsBDH2-NADH binding isotope effect data (dataset)
Pecaver, E. (Creator), Zickuhr, G. M. (Creator), Harrison, D. (Creator) & Guimaraes da Silva, R. (Creator), University of St Andrews, 27 Nov 2025
DOI: 10.17630/821f4347-65de-46d0-9459-e01b1261f9b0
Dataset
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Human 2'-deoxynucleoside 5'-phosphate N-hydrolase 1: mechanism of 2'-deoxyuridine 5'-monophosphate hydrolysis (dataset)
Devi, S. (Creator), Carberry, A. E. (Creator), Zickuhr, G. M. (Creator), Dickson, A. (Creator), Harrison, D. J. (Creator) & Guimaraes da Silva, R. (Creator), Protein Data Bank (PDB), 2023
DOI: 10.2210/pdb8osc/pdb, http://doi.org/10.2210/pdb8os9/pdb
Dataset
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Clear Cell Renal Cell Carcinoma Patient-Derived Tumoroids characterisation by Spatial Mass Spectrometry, Histology and Multiplex Immunofluorescence
Zickuhr, G. M. (Creator), Abdullah, H. (Creator), Um, I. (Creator), Laird, A. (Creator), Mullen, P. (Creator), Harrison, D. (Creator), Dickson, A. (Creator) & Ross, K. (Creator), EMBL-EBI, 22 Feb 2025
DOI: 10.6019/S-BIAD1661, https://www.ebi.ac.uk/biostudies/bioimages/studies/S-BIAD1661
Dataset
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Spatial Mass Spectrometry with Whole Slide Multiplex Immunofluorescence in Clear Cell Renal Cell Carcinoma
Ross, K. (Creator), Zickuhr, G. M. (Creator), Um, I. H. (Creator), Harrison, D. J. (Creator) & Dickson, A. (Creator), EMBL-EBI, 29 Aug 2024
DOI: 10.6019/S-BIAD1346, https://www.ebi.ac.uk/biostudies/bioimages/studies/S-BIAD1346
Dataset