Research output per year
Research output per year
Personal profile
Research overview
I retired from the University in 2020 and maintain an Emeritus position. From 2014-2019 I was Master and Deputy Principal, and for nine months in 2016 I was also acting Principal and Vice Chancellor. My research interests are now maintained through a University spinout company, Pneumagen, formed in 2016. This arose from having studied the structural biology of sialidases (or neuraminidases) for several decades. We engineered mutlivalent forms of carbohydrate-binding modules specific for sialic acid, a key component of the receptor used by the influenza virus, parainfluenza virus, some coronaviruses and pneumococci. In animal studies, these have shown protection against a variety of respiratory viruses, inclding influenza virus, respiratory syncytial virus and SARS-CoV-2. The lead biologic, Neumifil, is currently undergoing Phase 2 clincial studies. The company's research group is based in my old research space in BSRC.
Industrial relevance
Structure-based drug design of anti-microbials
Academic/Professional Qualification
B.Sc., Physics 1st Class; Ph.D.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where Garry Lindsay Taylor is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design
Cowton, V. M., Owsianka, A. M., Fadda, V., Ortega-Prieto, A. M., Cole, S. J., Potter, J. A., Skelton, J. K., Jeffrey, N., Di Lorenzo, C., Dorner, M., Taylor, G. L. & Patel, A. H., 8 Jan 2021, In: npj Vaccines. 6, 10 p., 7.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)10 Downloads (Pure) -
Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus
Owen, C. D., Tailford, L. E., Monaco, S., Šuligoj, T., Vaux, L., Lallement, R., Khedri, Z., Yu, H., Lecointe, K., Walshaw, J., Tribolo, S., Horrex, M., Bell, A., Chen, X., Taylor, G. L., Varki, A., Angulo, J. & Juge, N., 19 Dec 2017, In: Nature Communications. 8, p. 1-15 15 p., 2196.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Citations (Scopus)7 Downloads (Pure) -
PRIMA-1Met suppresses colorectal cancer independent of p53 by targeting MEK
Lu, T., Zou, Y., Xu, G., Potter, J. A., Taylor, G. L., Duan, Q., Yang, Q., Xiong, H., Qiu, H., Ye, D., Zhang, P., Yu, S., Yuan, X., Zhu, F., Wang, Y. & Xiong, H., 27 Oct 2016, In: Oncotarget. 7, 50, p. 83017-83030 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)4 Downloads (Pure) -
Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation
Tailford, L. E., Owen, C. D., Walshaw, J., Crost, E. H., Hardy-Goddard, J., Le Gall, G., de Vos, W. M., Taylor, G. L. & Juge, N., 8 Jul 2015, In: Nature Communications. 6, 12 p., 7624.Research output: Contribution to journal › Article › peer-review
Open AccessFile132 Citations (Scopus)11 Downloads (Pure) -
Immunomodulatory Compounds
Taylor, G. L. (Inventor) & Connaris, H. (Inventor), 30 Jul 2015, IPC No. A61K31/74, Patent No. WO2015110831 (A1)Research output: Patent
Datasets
-
Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus (dataset)
Owen, C. D. (Creator), Tailford, L. E. (Creator), Monaco, S. (Creator), Šuligoj, T. (Creator), Vaux, L. (Creator), Lallement, R. (Creator), Khedri, Z. (Creator), Yu, H. (Creator), Lecointe, K. (Creator), Walshaw, J. (Creator), Tribolo, S. (Creator), Horrex, M. (Creator), Bell, A. (Creator), Chen, X. (Creator) & Taylor, G. L. (Creator), Protein Data Bank (PDB), 2 May 2018
http://www.rcsb.org/pdb/results/results.do?tabtoshow=Current&qrid=251C1859 and 3 more links, http://dx.doi.org/10.2210/pdb6ER2/pdb, http://dx.doi.org/10.2210/pdb6ER3/pdb, http://dx.doi.org/10.2210/pdb6ER4/pdb (show fewer)
Dataset
Projects
- 14 Finished
-
Cunningham Trust: Combating Respiratory Virus infections - Novel Immunomodulatory Proteins
Taylor, G. L. (PI) & Connaris, H. (CoI)
1/03/14 → 31/08/16
Project: Standard
-
MRC Research Grant: Multivalent proteins for the prophylaxis of influenza
Taylor, G. L. (PI) & Connaris, H. (CoI)
1/01/14 → 31/12/14
Project: Standard
-
Multivalent theraputic proteins: Multivalent theraputic proteins for influenza
Taylor, G. L. (PI) & Connaris, H. (CoI)
1/06/11 → 31/07/13
Project: Standard
-
Sialoglyco2010 Potsdam
Taylor, G. L. (Keynote/Plenary speaker)
21 Aug 2010 → 26 Aug 2010Activity: Talk or presentation types › Invited talk
-
External Examiner for Biochemistry Degree
Taylor, G. L. (External examiner)
2010 → 2013Activity: Examination types › External examination
-
Brisbane Biological and Organic Chemistry Symposium
Taylor, G. L. (Keynote/Plenary speaker)
27 Nov 2009Activity: Talk or presentation types › Invited talk
-
From bacterial neuraminidases to new therapies for influenza and parainfluenza
Taylor, G. L. (Speaker)
6 Nov 2009Activity: Talk or presentation types › Invited talk
-
Structural studies on cholera pathogenicity factors
Taylor, G. L. (Speaker)
23 Apr 2009Activity: Talk or presentation types › Invited talk
Prizes
-
Fellow of the Royal Society of Edinburgh,
Taylor, G. L. (Recipient), 2005
Prize: Election to learned society
-
Honorary Visiting Professor at Nanlou Respiratory Diseases Department, PLA General Hospital, Beijing
Taylor, G. L. (Recipient), 2012
Prize: National/international honour
-
Peter Gallagher Memorial Glycomics Scholar
Taylor, G. L. (Recipient), 4 Oct 2010
Prize: National/international honour