Research output per year
Research output per year
Personal profile
Research overview
Molecular genetics of human breast cancer
Research concentrates on the phenomenon of familial cancers, particularly of the breast. It includes: participation in 'cancer family' clinics in Dundee and Edinburgh for assessment of risk to members of such families, investigation of interactions between genetic and environmental risk factors, and evaluation of screening and intervention strategies. Laboratory work concentrates on characterisation of mutations predisposing to breast and other cancers, particularly in the BRCA 1 and BRCA 2 genes. Questions addressed include: the frequencies of specific mutations in the Scottish population, (compared with others throughout the world), the clinical consequences of particular mutations, and the biochemical/cellular effects of gene inactivation or alteration.
Academic/Professional Qualification
M.B.Ch.B; Ph.D., University of Edinburgh; D.Sc., University of Edinburgh
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Why do women not return family history forms when referred to breast cancer genetics services? A mixed-method study
Hanning, K., Steel, C. M., Goudie, D., McLeish, L., Dunlop, J., Myring, J., Sullivan, F., Berg, J., Humphris, G. M. & Ozakinci, G., Oct 2015, In: Health Expectations. 18, 5, p. 1735-1743Research output: Contribution to journal › Article › peer-review
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Monitoring phyto-oestrogen exposure in patients with breast cancer after diagnosis
Gilmour, A., Ritchie, M. R., Mackinnon, L. J., Wong, V., Charlton, C., Steel, C. M., Gates, S. E. E., Smith, J. & Gibbs, T. J., 2007, In: Proceedings of the Nutrition Society . 66, p. 31A-31A 1 p.Research output: Contribution to journal › Article › peer-review
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Provision of breast cancer risk information to women at the lower end of the familial risk spectrum
Ozakinci, G., Humphris, G. & Steel, M., Dec 2007, In: Community Genetics. 10, 1, p. 41-44 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Surveillance for familial breast cancer: Differences in outcome according to BRCA mutation status
Moller, P., Evans, D., Reis, M., Gregory, H., Anderson, E., Maehle, L., Lalloo, F., Howell, A., Apold, J., Clark, N., Lucassen, A. & Steel, C. M., 1 Sept 2007, In: International Journal of Cancer. 121, 5, p. 1017-1020 4 p.Research output: Contribution to journal › Article › peer-review
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Analysis of referrals to a multi-disciplinary breast cancer genetics clinic: practical and economic considerations
Reis, M. M., Young, D., McLeish, L., Goudie, D., Cook, A., Sullivan, F., Vysny, H., Fordyce, A., Black, R., Tavakoli, M. & Steel, M., Nov 2006, In: Familial Cancer. 5, 4, p. 297-303 7 p.Research output: Contribution to journal › Article › peer-review
Activities
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Honorary Consultant (Medical Genetics), Lothian and Tayside Health Boards (External organisation)
Steel, C. M. (Participant)
1994 → …Activity: Membership types › Membership of public/government advisory/policy group or panel
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Steering Group, Scottish Molecular Genetics Consortium (External organisation)
Steel, C. M. (Participant)
1994 → …Activity: Membership types › Membership of research network
Prizes
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Fellow of the Academy of Medical Sciences,
Steel, C. M. (Recipient), 1994
Prize: Election to learned society
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Fellow of the Royal College of Pathologists,
Steel, C. M. (Recipient), 1994
Prize: Election to learned society
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Fellow of the Royal College of Physicians of Edinburgh,
Steel, C. M. (Recipient), 1994
Prize: Election to learned society
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Fellow of the Royal College of Surgeons of England,
Steel, C. M. (Recipient), 1994
Prize: Election to learned society
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Fellow of the Royal Society of Edinburgh,
Steel, C. M. (Recipient), 1994
Prize: Election to learned society