Andy Lynch

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Andy Lynch

Prof

 https://orcid.org/0000-0002-7876-7338

  • KY16 9SS

    United Kingdom

Accepting Postgraduate Research Students

Personal profile

Profile Keywords

Statistics; Cancer; Genomics; Computational Biology

Biography

Professor Lynch joined the University of St Andrews in 2017 after 15 years at the University of Cambridge working in the Department of Public Health and Primary Care, The Department of Oncology and for the most part the Cancer Research UK Cambridge Institute. Divided between the Schools of Medicine, and Mathematics and Statistics, in St Andrews his research is divided between the development and application of analysis methods - typically in the context of cancer genomics.

Research overview

Professor Lynch works on the development and application of analysis methods for cancer sequencing data. This includes questions of experimental design within cancer genomics, fundamental questions regarding the extraction of data (and uncertainty) from modern biological methods, methods for answering biological and clinical questions in new ways, and applications to multiple cancer types (including Prostate, Glioblastoma,  Oesophageal, Breast, Renal, Ovarian and Lung). 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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Collaborations and top research areas from the last five years

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View all 152 research outputs

  • Telomerecat: The telomere computational analysis tool

    Farmery, J. (Creator), Smith, M. (Creator) & Lynch, A. (Creator), GitHub, 9 Dec 2017

    https://github.com/jhrf/telomerecat

    Dataset

  • Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets (dataset)

    Wedge, D. C. (Creator), Gundem, G. (Creator), Mitchell, T. (Creator), Woodstock, D. J. (Creator), Martincorena, I. (Creator), Ghori, M. (Creator), Zamora, J. (Creator), Butler, A. (Creator), Whitaker, H. (Creator), Kote-Jarai, Z. (Creator), Alexandrov, L. B. (Creator), Van Loo, P. (Creator), Massie, C. E. (Creator), Dentro, S. (Creator), Warren, A. Y. (Creator), Verrill, C. (Creator), Berney, D. M. (Creator), Dennis, N. (Creator), Merson, S. (Creator), Hawkins, S. (Creator), Howat, W. (Creator), Lu, Y.-J. (Creator), Lambert, A. (Creator), Kay, J. (Creator), Kremeyer, B. (Creator), Karaszi, K. (Creator), Luxton, H. (Creator), Camacho, N. (Creator), Marsden, L. (Creator), Edwards, S. (Creator), Matthews, L. (Creator), Bo, V. (Creator), Leongamornlert, D. (Creator), McLaren, S. (Creator), Ng, A. (Creator), Yu, Y. (Creator), Zhang, H. (Creator), Dadaev, T. (Creator), Thomas, S. (Creator), Easton, D. F. (Creator), Ahmed, M. (Creator), Bancroft, E. (Creator), Fisher, C. (Creator), Livni, N. (Creator), Nicol, D. (Creator), Tavaré, S. (Creator), Gill, P. (Creator), Greenman, C. (Creator), Khoo, V. (Creator), Van As, N. (Creator), Kumar, P. (Creator), Ogden, C. (Creator), Cahill, D. (Creator), Thompson, A. (Creator), Meyer, E. (Creator), Rowe, E. (Creator), Dudderidge, T. (Creator), Gnanapragasam, V. (Creator), Shah, N. C. (Creator), Raine, K. (Creator), Jones, D. (Creator), Menzies, A. (Creator), Stebbings, L. (Creator), Teague, J. (Creator), Hazell, S. (Creator), Corbishley, C. (Creator), de Bono, J. (Creator), Attard, G. (Creator), Isaacs, W. (Creator), Visakorpi, T. (Creator), Fraser, M. (Creator), Boutros, P. C. (Creator), Bristow, R. G. (Creator), Workman, P. (Creator), Sander, C. (Creator), Hamdy, F. C. (Creator), Futreal, A. (Creator), McDermott, U. (Creator), Al-Lazikani, B. (Creator), Lynch, A. G. (Data Collector), Bova, G. S. (Creator), Foster, C. S. (Creator), Brewer, D. S. (Creator), Neal, D. E. (Creator), Cooper, C. S. (Creator) & Eeles, R. A. (Creator), European Genome-phenome Archive (EGA), 16 Apr 2018

    https://www.ebi.ac.uk/ega/studies/EGAS00001000262

    Dataset

  • Mutation calls for 'A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy'

    Noorani, A. (Creator), Bornschein, J. (Creator), Lynch, A. (Creator), Secrier, M. (Creator), Achilleos, A. (Creator), Eldridge, M. (Creator), Bower, L. (Creator), Weaver, J. M. J. (Creator), Crawte, J. (Creator), Ong, C.-A. (Creator), Shannon, N. (Creator), MacRae, S. (Creator), Grehan, N. (Creator), Nutzinger, B. (Creator), O'Donovan, M. (Creator), Hardwick, R. (Creator), Tavaré, S. (Creator) & Fitzgerald, R. C. (Creator), International Cancer Genome Consortium (ICGC), 2017

    https://dcc.icgc.org/projects/ESAD-UK

    Dataset

  • Whole-genome sequencing of nine esophageal adenocarcinoma cell lines (dataset)

    Lynch, A. (Creator), European Nucleotide Archive (ENA), 2016

    http://www.ebi.ac.uk/ena/data/view/PRJEB14018

    Dataset

  • A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing (dataset)

    Alioto, T. S. (Creator), Buchhalter, I. (Creator), Derdak, S. (Creator), Hutter, B. (Creator), Eldridge, M. D. (Creator), Hovig, E. (Creator), Heisler, L. E. (Creator), Beck, T. A. (Creator), Simpson, J. T. (Creator), Tonon, L. (Creator), Sertier, A.-S. (Creator), Patch, A.-M. (Creator), Jaeger, N. (Creator), Ginsbach, P. (Creator), Drews, R. (Creator), Paramasivam, N. (Creator), Kabbe, R. (Creator), Chotewutmontri, S. (Creator), Diessl, N. (Creator), Previti, C. (Creator), Schmidt, S. (Creator), Brors, B. (Creator), Feuerbach, L. (Creator), Heinold, M. (Creator), Groebner, S. (Creator), Korshunov, A. (Creator), Tarpey, P. S. (Creator), Butler, A. P. (Creator), Hinton, J. (Creator), Jones, D. (Creator), Menzies, A. (Creator), Raine, K. (Creator), Shepherd, R. (Creator), Stebbings, L. (Creator), Teague, J. W. (Creator), Ribeca, P. (Creator), Castro Giner, F. (Creator), Beltran, S. (Creator), Raineri, E. (Creator), Dabad, M. (Creator), Heath, S. C. (Creator), Gut, M. (Creator), Denroche, R. E. (Creator), Harding, N. J. (Creator), Yamaguchi, T. N. (Creator), Fujimoto, A. (Creator), Nakagawa, H. (Creator), Quesada, C. (Creator), Valdes-Mas, R. (Creator), Nakken, S. (Creator), Vodak, D. (Creator), Bower, L. (Creator), Lynch, A. (Creator), Anderson, C. L. (Creator), Waddell, N. (Creator), Pearson, J. V. (Creator), Grimmond, S. M. (Creator), Peto, M. (Creator), Spellman, P. (Creator), He, M. (Creator), Kandoth, C. (Creator), Lee, S. (Creator), Zhang, J. (Creator), Letourneau, L. (Creator), Ma, S. (Creator), Seth, S. (Creator), Torrents, D. (Creator), Xi, L. (Creator), Wheeler, D. A. (Creator), Lopez-Otin, C. (Creator), Campo, E. (Creator), Campbell, P. J. (Creator), Boutros, P. C. (Creator), Puente, X. S. (Creator), Gerhard, D. S. (Creator), Pfister, S. M. (Creator), McPherson, J. D. (Creator), Hudson, T. J. (Creator), Schlesner, M. (Creator), Lichter, P. (Creator), Eils, R. (Creator), Jones, D. T. W. (Creator) & Gut, I. G. (Creator), European Genome-phenome Archive (EGA), 2015

    https://www.ebi.ac.uk/ega/studies/EGAS00001001539

    Dataset

View all 20 datasets/software