Research output per year
Research output per year
- 1 - 50 out of 257 results
Search results
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2024
Adverse drug reactions resulting from the use of chiral medicines amoxicillin, amoxicillin-clavulanic acid, and ceftriaxone: a mixed prospective-retrospective cohort study
Mwamwitwa, K. W., Bukundi, E. M., Maganda, B. A., Munishi, C., Fimbo, A. M., Buma, D., Muro, E. P., Sabiiti, W., Shewiyo, D. H., Shearer, M. C., Smith, A. D. & Kaale, E. A., 15 Sept 2024, (E-pub ahead of print) In: INQUIRY: The Journal of Health Care Organization, Provision, and Financing. 61, 18 p.Research output: Contribution to journal › Article › peer-review
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De-epimerizing DyKAT of β-lactones generated by isothiourea-catalysed enantioselective [2 + 2] cycloaddition
Conboy, A., Goodfellow, A. S., Kasten, K., Dunne, J., Cordes, D. B., Buehl, M. & Smith, A. D., 24 Apr 2024, (E-pub ahead of print) In: Chemical Science. 15, 23, p. 8896-8904Research output: Contribution to journal › Article › peer-review
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Enantioselective synthesis in continuous flow: polymer supported isothiourea-catalyzed enantioselective Michael addition-cyclization with α-azol-2-ylacetophenones
Zhou, Z., Kasten, K., Kang, T., Cordes, D. B. & Smith, A. D., 17 May 2024, In: Organic Process Research & Development. 28, 5, p. 2041–2049Research output: Contribution to journal › Article › peer-review
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Enantioselective synthesis of tetra-substituted 3- hydroxyphthalide esters by isothiourea-catalysed acylative dynamic kinetic resolution
Agrawal, S. K., Majhi, P., Goodfellow, A. S., Tak, R., Cordes, D. B., McKay, A., Kasten, K., Buehl, M. & Smith, A. D., 6 May 2024, (Accepted/In press) In: Angewandte Chemie International Edition.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalysed acylative dynamic kinetic resolution of tetra-substituted morpholinone and benzoxazinone lactols
Zhu, H., Manchado, A., Farah, A. O., McKay, A., Cordes, D. B., Cheong, P.H.-Y., Kasten, K. & Smith, A. D., 6 May 2024, (Accepted/In press) In: Angewandte Chemie International Edition.Research output: Contribution to journal › Article › peer-review
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One-pot access to functionalised malamides via organocatalytic enantioselective formation of spirocyclic β-lactone-oxindoles and double ring-opening.
Nimmo, A., Kasten, K., White, G., Roeterdink, J., McKay, A., Cordes, D. B. & Smith, A. D., 31 Jul 2024, In: Molecules. 29, 15, 16 p., 3635.Research output: Contribution to journal › Article › peer-review
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α-Phenylthioaldehydes for the effective generation of acyl azolium and azolium enolate intermediates
Ewing, P., Majhi, P., Prentice, C., Young, C. M., Van Rees, K., Arnold, P., Zysman-Colman, E. & Smith, A. D., 14 May 2024, In: Chemical Science. 24, 15, p. 9369-9375Research output: Contribution to journal › Article › peer-review
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2023
Access to a diverse array of bridged benzo[1,5]oxazocine and benzo[1,4]diazepine structures
Sherborne, G. J., Diène, C., Kemmitt, P. & Smith, A. D., 23 Nov 2023, (E-pub ahead of print) In: Organic Letters. Articles ASAPResearch output: Contribution to journal › Article › peer-review
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Benzophenone as a cheap and effective photosensitizer for the photocatalytic synthesis of dimethyl cubane-1,4-dicarboxylate
Prentice, C., Martin, A. E., Morrison, J. J., Smith, A. D. & Zysman-Colman, E., 28 Apr 2023, In: Organic & Biomolecular Chemistry. 21, 16, p. 3307-3310 4 p.Research output: Contribution to journal › Article › peer-review
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Enantioselective isothiourea-catalysed reversible Michael addition of aryl esters to 2-benzylidene malononitriles
Nimmo, A., Bitai, J., Young, C. M., McLaughlin, C., Slawin, A. M. Z., Cordes, D. B. & Smith, A. D., 21 Jul 2023, In: Chemical Science. 14, 27, p. 7537-7544 8 p.Research output: Contribution to journal › Article › peer-review
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Intramolecular hydrogen bond activation for kinetic resolution of furanone derivatives by an organocatalyzed [3+2] asymmetric cycloaddition
Valle-Amores, M. A., Feberero, C., Martin-Somer, A., Díaz-Tendero, S., Smith, A. D., Fraile, A. & Alemán, J., 11 Oct 2023, (E-pub ahead of print) In: Organic Chemistry Frontiers. Advance article, 11 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed enantioselective functionalisation of glycine Schiff base aryl esters via 1,6- and 1,4-additions
Stockhammer, L., Craik, R., Monkowius, U., Cordes, D. B., Smith, A. D. & Waser, M., 3 Jul 2023, In: Chemistry Europe. 1, 1, 9 p., e202300015.Research output: Contribution to journal › Article › peer-review
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Multi-resonant thermally activated delayed fluorescent (MR-TADF) compounds as photocatalysts
Prentice, C., Morrison, J., Smith, A. D. & Zysman-Colman, E., 9 Jan 2023, In: Chemistry - A European Journal. 29, 2, 9 p., e202202998.Research output: Contribution to journal › Article › peer-review
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Probing regio- and enantioselectivity in the formal [2+2] cycloaddition of C(1)-alkyl ammonium enolates with - and ,-substituted tri-fluoromethylenones
Wang, Y., Young, C. M., Cordes, D. B., Slawin, A. M. Z. & Smith, A. D., 16 Jun 2023, In: The Journal of Organic Chemistry. 88, 12, p. 7784-7799 16 p.Research output: Contribution to journal › Article › peer-review
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Rate and equilibrium constants for the addition of triazolium salt derived N-heterocyclic carbenes to heteroaromatic aldehydes
Duan, Z., Young, C. M., Zhu, J., Slawin, A., O'Donoghue, A. C. & Smith, A. D., 7 Jan 2023, In: Chemical Science. 14, 1, p. 162-170 8 p.Research output: Contribution to journal › Article › peer-review
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Understanding divergent substrate stereoselectivity in the isothiourea-catalysed conjugate addition of cyclic α-substituted β-ketoesters to α,β-unsaturated aryl esters
Yuan, D., Goodfellow, A. S., Duan, Z., Kang, T., Kasten, K., Cordes, D. B., McKay, A., Buehl, M., Boyce, G. R. & Smith, A. D., 28 Dec 2023, In: Chemical Science. 14, 48, p. 14146-14156 11 p.Research output: Contribution to journal › Article › peer-review
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Unveiling the impact of a CF2 motif in the isothiourea catalyst skeleton: evaluating C(3)-F2-HBTM and its catalytic activity
Westwood, M., Kasten, K., Stockhammer, L., del Río-Rodríguez, R., Fernández-Salas, J. A., Eitzinger, A., Slawin, A. M. Z., Waser, M., Alémán, J., Ofial, A. R. & Smith, A. D., 31 Dec 2023, In: ARKIVOC. 2024, 4, 23 p., 202312093.Research output: Contribution to journal › Article › peer-review
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Visible light-mediated cyclisation reaction for the synthesis of highly-substituted tetrahydroquinolines and quinolines
Sherborne, G. J., Kemmitt, P., Prentice, C., Zysman-Colman, E., Smith, A. D. & Fallan, C., 9 Jan 2023, In: Angewandte Chemie International Edition. 62, 2, 10 p., e202207829.Research output: Contribution to journal › Article › peer-review
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2022
A desilylative approach to alkyl substituted C(1)-ammonium enolates: application in enantioselective [2+2] cycloadditions
Wang, Y., Young, C. M., Liu, H., Hartley, W., Wienhold, M., Cordes, D. B., Slawin, A. M. Z. & Smith, A. D., 12 Sept 2022, In: Angewandte Chemie International Edition. 61, 38, 9 p., e202208800.Research output: Contribution to journal › Article › peer-review
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Arylboronic acid-catalyzed racemization of secondary and tertiary alcohols
Boyce, G., Musolino, S. F., Yang, J., Smith, A. D. & Taylor, J., 7 Oct 2022, In: The Journal of Organic Chemistry. 87, 19, p. 13367-13374 8 p.Research output: Contribution to journal › Article › peer-review
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Cooperative palladium/isothiourea catalyzed enantioselective formal (3+2) cycloaddition of vinylcyclopropanes and α,β-unsaturated esters
Bitai, J., Nimmo, A., Slawin, A. M. Z. & Smith, A. D., 20 Jun 2022, In: Angewandte Chemie International Edition. 61, 25, 9 p., e202202621.Research output: Contribution to journal › Article › peer-review
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Dual NHC/photoredox catalytic synthesis of 1,4-diketones using an MR-TADF photocatalyst (DiKTa)
Prentice, C., Morrison, J., Zysman-Colman, E. & Smith, A. D., 21 Dec 2022, In: Chemical Communications. 58, 98, p. 13624-13627 4 p.Research output: Contribution to journal › Article › peer-review
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Effectiveness of a structured stimulated spontaneous safety monitoring of medicines reporting program in strengthening pharmacovigilance system in Tanzania
Mwamwitwa, K., Fimbo, A., Bukundi , E., Nkayamba, A., Buma , D., Muro, E., Maganda, B., Shewiyo, D., Shearer, M., Smith, A. D. & Kaale , E., 27 Sept 2022, In: Scientific Reports. 12, 11 p., 16131.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalysed enantioselective radical conjugate addition under batch and flow conditions
del Río-Rodríguez, R., Westwood, M., Sicignano, M., Juhl, M., Fernández-Salas, J. A., Alemán, J. & Smith, A. D., 4 Jul 2022, In: Chemical Communications. 58, 52, p. 7277-7280 4 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed [2+2] cycloaddition of C(1)-ammonium enolates and N-alkyl isatins
Abdelhamid, Y., Kasten, K., Dunne, J., Hartley, W., Young, C. M., Cordes, D. B., Slawin, A. M. Z., Ng, S. & Smith, A. D., 18 Jul 2022, (E-pub ahead of print) In: Organic Letters. Articles ASAP, 6 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed enantioselective Michael addition of malonates to α,β-unsaturated aryl esters
Wu, J., Young, C. M., Watts, A. A., Slawin, A. M. Z., Boyce, G., Buehl, M. & Smith, A. D., 10 Jun 2022, In: Organic Letters. 24, 22, p. 4040-4045 6 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed formal enantioselective conjugate addition of benzophenone imines to ß-fluorinated a,ß-unsaturated esters
Lapetaje, J., Young, C. M., Shu, C. & Smith, A. D., 21 Jun 2022, In: Chemical Communications. 58, 49, p. 6886-6889 4 p.Research output: Contribution to journal › Article › peer-review
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Scope, limitations and mechanistic analysis of the HyperBTM-catalyzed acylative kinetic resolution of tertiary heterocyclic alcohols
Smith, S., Greenhalgh, M. D., Feoktistova, T., Walden, D. M., Taylor, J. E., Cordes, D. B., Slawin, A. M. Z., Cheong, P.H.-Y. & Smith, A. D., 11 Jan 2022, In: European Journal of Organic Chemistry. p. 30-43 14 p., e202101111.Research output: Contribution to journal › Article › peer-review
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The role of the fused ring in bicyclic triazolium organocatalysts: kinetic, X-ray and DFT insights
Zhu, J., Moreno, I., Quinn, P., Yufit, D. S., Song, L., Young, C. M., Duan, Z., Tyler, A. R., Waddell, P. G., Hall, M. J., Probert, M. R., Smith, A. D. & O'Donoghue, A. C., 18 Mar 2022, In: The Journal of Organic Chemistry. 87, 6, p. 4241-4253Research output: Contribution to journal › Article › peer-review
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2021
Catalytic enantioselective synthesis of 1,4-dihydropyridines via the addition of C(1)-ammonium enolates to pyridinium salts
McLaughlin, C., Bitai, J., Barber, L., Slawin, A. & Smith, A. D., 6 Aug 2021, (E-pub ahead of print) In: Chemical Science. Advance Article, 11 p.Research output: Contribution to journal › Article › peer-review
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Enantioselective synthesis of α-aryl-β2-amino-esters by cooperative isothiourea and Brønsted acid catalysis
Zhao, F., Shu, C., Young, C. M., Carpenter-Warren, C., Slawin, A. M. Z. & Smith, A. D., 11 May 2021, In: Angewandte Chemie International Edition. 60, 21, p. 11892-11900 10 p.Research output: Contribution to journal › Article › peer-review
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Horeau amplification in the sequential acylative kinetic resolution of (±)-1,2-diols and (±)-1,3-diols in flow
Brandolese, A., Greenhalgh, M. D., Desrues, T., Liu, X., Qu, S., Bressy, C. & Smith, A. D., 28 Apr 2021, In: Organic & Biomolecular Chemistry. 19, 16, p. 3620-3627 8 p.Research output: Contribution to journal › Article › peer-review
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In vitro and in cellulo anti-diabetic activity of AuI- and AuIII-isothiourea complexes
Fayyaz, S., Shaikh, M., Gasperini, D., Nolan, S. P., Smith, A. D. & Choudhary, M. I., 12 May 2021, (E-pub ahead of print) In: Inorganic Chemistry Communications. In press, 108666.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed enantioselective α-alkylation of esters via 1,6-conjugate addition to para-quinone methides
Arokianathar, J. N., Hartley, W., McLaughlin, C., Greenhalgh, M. D., Stead, D., Ng, S., Slawin, A. M. Z. & Smith, A. D., 20 Oct 2021, In: Molecules. 26, 21, 13 p., 6333.Research output: Contribution to journal › Article › peer-review
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Kinetic and structure-activity studies of the triazolium Ion-catalyzed intramolecular stetter reaction
Collett, C. J., Young, C. M., Massey, R. S., O'Donoghue, A. & Smith, A. D., 15 Jul 2021, In: European Journal of Organic Chemistry. 2021, 26, p. 3670-3675 7 p., 202100384.Research output: Contribution to journal › Article › peer-review
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Ultrarapid cerium(III)–NHC catalysts for high molar mass cyclic polylactide
Kerr, R. W. F., Ewing, P., Raman, S. K., Smith, A. D., Williams, C. K. & Arnold, P. L., 15 Jan 2021, (E-pub ahead of print) In: ACS Catalysis. 11, p. 1563-1569Research output: Contribution to journal › Article › peer-review
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α,β-Unsaturated acyl ammonium species as reactive intermediates in organocatalysis: an update
Bitai, J., Westwood, M. & Smith, A. D., 1 Mar 2021, (E-pub ahead of print) In: Organic & Biomolecular Chemistry. Advance Article, 19 p.Research output: Contribution to journal › Review article › peer-review
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2020
A mechanistically and operationally simple route to metal-N-heterocyclic carbene (NHC) Complexes
Nolan, S. P., Tzouras, N., Nahra, F., Falivene, L., Cavallo, L., Saab, M., Van Hecke, K., Collado, A., Collett, C., Smith, A. D. & Cazin, C. S. J., 12 Mar 2020, (E-pub ahead of print) In: Chemistry - A European Journal. Early ViewResearch output: Contribution to journal › Article › peer-review
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A retrospective cross-sectional study to determine chirality status of registered medicines in Tanzania
Mwamwitwa, K. W., Kaibere, R. M., Fimbo, A. M., Sabitii, W., Ntinginya, N. E., Mmbaga, B. T., Shewiyo, D. H., Shearer, M. C., Smith, A. D. & Kaale, E. A., 20 Oct 2020, In: Scientific Reports. 10, 1, 11 p., 17834.Research output: Contribution to journal › Article › peer-review
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Continuous flow preparation of enantiomerically pure BINOL(s) by acylative kinetic resolution
Lai, J., Neyyappadath, R. M., Smith, A. D. & Pericàs, M. A., 27 Jan 2020, (E-pub ahead of print) In: Advanced Synthesis & Catalysis. Early ViewResearch output: Contribution to journal › Article › peer-review
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Exploring the scope of tandem palladium and isothiourea relay catalysis for the synthesis of α-amino acid derivatives
Bitai, J., Slawin, A. M. Z., Cordes, D. B. & Smith, A. D., 25 May 2020, In: Molecules. 25, 10, 13 p., 2463.Research output: Contribution to journal › Article › peer-review
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Generation and reactivity of C(1)-ammonium enolates using isothiourea catalysis
McLaughlin, C. & Smith, A. D., 10 Nov 2020, (E-pub ahead of print) In: Chemistry - A European Journal. Early ViewResearch output: Contribution to journal › Review article › peer-review
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Isothiourea-catalyzed acylative kinetic resolution of tertiary α-hydroxy esters
Qu, S., Smith, S., Laina-Martin, V., Neyyappadath, R., Greenhalgh, M. D. & Smith, A. D., 14 Sept 2020, In: Angewandte Chemie International Edition. 59, 38, p. 16572-16578 8 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed atropselective acylation of biaryl phenols via sequential desymmetrization/kinetic resolution
Munday, E. S., Grove, M., Feoktistova, T., Brueckner, A. C., Walden, D., Young, C. M., Slawin, A. M. Z., Campbell, A., Cheong, P.H.-Y. & Smith, A. D., 11 Mar 2020, (E-pub ahead of print) In: Angewandte Chemie International Edition. Early ViewResearch output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed enantioselective synthesis of tetrahydro-α-carbolinones
Liu, H., Slawin, A. M. M. & Smith, A. D., 6 Feb 2020, (E-pub ahead of print) In: Organic Letters. Articles ASAPResearch output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed functionalization of pyrrolyl- and indolylacetic acid: enantioselective synthesis of dihydropyridinones and one-pot synthesis of pyridinones
Zhang, S., Bacheley, L., Young, C. M., Stark, D. G., O'Riordan, T., Slawin, A. M. Z. & Smith, A. D., Oct 2020, In: Asian Journal of Organic Chemistry. 9, 10, p. 1562-1566 5 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed synthesis of pyrrole- and indole-functionalized tetrasubstituted pyridines
Zhang, S., Hartley, W., Greenhalgh, M. D., Ng, S., Slawin, A. M. Z. & Smith, A. D., 18 Sept 2020, In: ChemCatChem. 12, 18, p. 4522-4525 5 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed transfer hydrogenation of α,β-unsaturated para-nitrophenyl esters
Wu, J., Young, C. M. & Smith, A. D., 13 Nov 2020, (E-pub ahead of print) In: Tetrahedron. In press, 131758.Research output: Contribution to journal › Article › peer-review
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Kinetic and structure-activity studies of the triazolium ion-catalysed benzoin condensation
Massey, R., Murray, J., Collett, C. J., Zhu, J., Smith, A. D. & O'Donoghue, A., 14 Dec 2020, (E-pub ahead of print) In: Organic & Biomolecular Chemistry. Advance article, 7 p.Research output: Contribution to journal › Article › peer-review
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Kinetic resolution and desymmetrization of alcohols and amines by nonenzymatic, enantioselective acylation
Frost, A. B., Greenhalgh, M. D., Munday, E. S., Musolino, S. F., Taylor, J. E. & Smith, A. D., 6 Dec 2020, (E-pub ahead of print) Organic Reaction. John Wiley & Sons, Ltd, p. 1-498 498 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter