Projects per year
Description
Nitroxides are widely used as probes and polarization transfer agents in spectroscopy and imaging.These applications require high stability towards reducing biological environments, as well as beneficial relaxation properties. Closed spirocyclohexyl nitroxides exhibit a dramatically improved stability towards reduction by ascorbate, while maintaining long relaxation times in EPR spectroscopy. This dataset contains raw files and analysis reports of 1HNMR, 13CNMR, HRMS, FTIR of all compounds synthesized for and used in work: Conformational tuning improves the stability of spirocyclic nitroxides with long paramagnetic relaxation times. Moreover, for nitroxides raw files of X-band CW-EPR spectra, kinetic runs based on CW-EPR spectra and Q-band EPR relaxation measurements are included. Dataset is completed with X-ray crystallography CIF files and reports.
| Date made available | 2022 |
|---|---|
| Publisher | DataverseNO |
Projects
- 2 Finished
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Enabling Shaped Pulse Capability: Enabling Shaped Pulse Capability for Superior Biological Structural Determination Using EPR Spectroscopy.
Lovett, J. E. (PI), Bode, B. E. (CoI), Penedo, C. (CoI), Pitt, S. J. (CoI), Schwarz-Linek, U. (CoI), Smith, G. M. (CoI), Watson, A. J. B. (CoI) & White, M. (CoI)
1/10/20 → 30/09/21
Project: Standard
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State of the art pulse EPR instrumentati: State of the art pulse EPR instrumentation for long range distance measurements in biomacromolecules
Smith, G. M. (PI), Bode, B. E. (CoI), Naismith, J. (CoI), Schiemann, O. (CoI) & White, M. (CoI)
1/09/12 → 31/08/17
Project: Standard
Research output
- 1 Article
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Conformational tuning improves the stability of spirocyclic nitroxides with long paramagnetic relaxation times
Sowiński, M. P., Gahlawat, S., Lund, B. A., Warnke, A.-L., Hopmann, K. H., Lovett, J. E. & Haugland, M. M., 5 Jun 2023, In: Communications Chemistry. 6, 1, 8 p., 111.Research output: Contribution to journal › Article › peer-review
Open AccessFile